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Identification of EphA7 BAC clone containing a long-range dorsal midline-specific enhancer

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dc.contributor.authorKim, Yujin-
dc.contributor.authorPark, Soochul-
dc.date.available2021-02-22T13:18:14Z-
dc.date.issued2011-02-
dc.identifier.issn1976-6696-
dc.identifier.issn1976-670X-
dc.identifier.urihttps://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/12644-
dc.description.abstractPrevious studies suggest that EphA7 plays a critical role in neural tube closure or cortical progenitor apoptosis. In this report, enhancer trap assay was used to modify various EphA7 BAC clones and screen a large genomic region spanning 570 kb downstream of the EphA7 gene. We found that the dorsal midline-specific EphA7 enhancer resides on the 457D20 EphA7 BAC clone and is localized to a 35 kb genomic region in between +345.7 kb to +379.8 kb downstream of the EphA7 transcription start site. Identification of the EphA7 BAC clone containing a long-range dorsal midline enhancer may constitute a useful tool for investigating the biological functions of EphA7 in vivo. [BMB reports 2011; 44(2): 113-117]-
dc.format.extent5-
dc.language영어-
dc.language.isoENG-
dc.publisherKOREAN SOCIETY BIOCHEMISTRY & MOLECULAR BIOLOGY-
dc.titleIdentification of EphA7 BAC clone containing a long-range dorsal midline-specific enhancer-
dc.typeArticle-
dc.publisher.location대한민국-
dc.identifier.doi10.5483/BMBRep.2011.44.2.113-
dc.identifier.scopusid2-s2.0-79952047905-
dc.identifier.wosid000287991400006-
dc.identifier.bibliographicCitationBMB REPORTS, v.44, no.2, pp 113 - 117-
dc.citation.titleBMB REPORTS-
dc.citation.volume44-
dc.citation.number2-
dc.citation.startPage113-
dc.citation.endPage117-
dc.type.docTypeArticle-
dc.identifier.kciidART001527797-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.subject.keywordPlusRECEPTOR-
dc.subject.keywordPlusEXPRESSION-
dc.subject.keywordPlusGENE-
dc.subject.keywordPlusMESENCEPHALON-
dc.subject.keywordPlusREGION-
dc.subject.keywordPlusSYSTEM-
dc.subject.keywordPlusMDK1-
dc.subject.keywordAuthorBacterial artificial chromosome-
dc.subject.keywordAuthorEnhancer-
dc.subject.keywordAuthorEphA7-
dc.subject.keywordAuthorTransgenic mice-
dc.identifier.urlhttp://koreascience.or.kr/article/JAKO201108863882199.page-
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