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New estrogenic compounds isolated from Broussonetia kazinoki
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Lee, Da Yeon | - |
| dc.contributor.author | Kim, Do Hee | - |
| dc.contributor.author | Lee, Hwa Jin | - |
| dc.contributor.author | Lee, YoungJoo | - |
| dc.contributor.author | Ryu, Kwang Hee | - |
| dc.contributor.author | Jung, Bo-In | - |
| dc.contributor.author | Song, Yun Seon | - |
| dc.contributor.author | Ryu, Jae-Ha | - |
| dc.date.available | 2021-02-22T13:47:44Z | - |
| dc.date.issued | 2010-06-15 | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.issn | 1464-3405 | - |
| dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/13186 | - |
| dc.description.abstract | Two new and two known compounds were identified as estrogenic constituents from Broussonetia kazinoki. Their structures were elucidated as broussonin A (1), tupichinol C (2), kazinol U (3), and (+)-(2R) kazinol I (4). They showed estrogenic activity with ligand-binding activity of estrogen receptor, transcriptional activity of estrogen-responsive element-luciferase reporter genes. They also control the cellular gene expression levels of estrogen-responsive genes. Phytoestrogens from B. kazinoki may have beneficial effects in the treatment of menopausal symptoms. (C) 2010 Elsevier Ltd. All rights reserved. | - |
| dc.format.extent | 4 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
| dc.title | New estrogenic compounds isolated from Broussonetia kazinoki | - |
| dc.type | Article | - |
| dc.publisher.location | 영국 | - |
| dc.identifier.doi | 10.1016/j.bmcl.2010.04.064 | - |
| dc.identifier.scopusid | 2-s2.0-77954216573 | - |
| dc.identifier.wosid | 000278208200068 | - |
| dc.identifier.bibliographicCitation | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.20, no.12, pp 3764 - 3767 | - |
| dc.citation.title | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| dc.citation.volume | 20 | - |
| dc.citation.number | 12 | - |
| dc.citation.startPage | 3764 | - |
| dc.citation.endPage | 3767 | - |
| dc.type.docType | Article | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | sci | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
| dc.subject.keywordPlus | BREAST | - |
| dc.subject.keywordPlus | RECEPTOR | - |
| dc.subject.keywordPlus | CANCER | - |
| dc.subject.keywordPlus | BETA | - |
| dc.subject.keywordPlus | CONSTITUENTS | - |
| dc.subject.keywordPlus | MECHANISMS | - |
| dc.subject.keywordPlus | COMPONENT | - |
| dc.subject.keywordPlus | FLAVANS | - |
| dc.subject.keywordPlus | ALPHA | - |
| dc.subject.keywordPlus | CELLS | - |
| dc.subject.keywordAuthor | Estrogen receptor | - |
| dc.subject.keywordAuthor | Phytoestrogen | - |
| dc.subject.keywordAuthor | Broussonetia kazinoki | - |
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