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Stereoselective synthesis of (+)-flutriafol
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Chang, Minsun | - |
| dc.contributor.author | Kim, Tae Hyun | - |
| dc.contributor.author | Kim, Hee-Doo | - |
| dc.date.available | 2021-02-22T14:33:34Z | - |
| dc.date.issued | 2008-06-30 | - |
| dc.identifier.issn | 0957-4166 | - |
| dc.identifier.issn | 1362-511X | - |
| dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/14232 | - |
| dc.description.abstract | The stereoselective synthesis of (+)-flutriafol, a triazole fungicide, has been accomplished in seven linear steps from (1S)-[(4R)-2,2-dimethyl-[1,3]-dioxotan-4-yl]-(4-methoxyphenyl)methanol in 15% overall yield. Diastereoselective nucleophilic 1,2-addition was employed as a key step for constructing the requisite chiral 1,2-diol for flutriafol. A high degree of 1,4-asymmetric induction could be realized via a chelation-controlled mechanism during the key alkylation step. (C) 2008 Elsevier Ltd. All rights reserved. | - |
| dc.format.extent | 5 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
| dc.title | Stereoselective synthesis of (+)-flutriafol | - |
| dc.type | Article | - |
| dc.publisher.location | 영국 | - |
| dc.identifier.doi | 10.1016/j.tetasy.2008.06.007 | - |
| dc.identifier.scopusid | 2-s2.0-46449100871 | - |
| dc.identifier.wosid | 000258046200018 | - |
| dc.identifier.bibliographicCitation | TETRAHEDRON-ASYMMETRY, v.19, no.12, pp 1504 - 1508 | - |
| dc.citation.title | TETRAHEDRON-ASYMMETRY | - |
| dc.citation.volume | 19 | - |
| dc.citation.number | 12 | - |
| dc.citation.startPage | 1504 | - |
| dc.citation.endPage | 1508 | - |
| dc.type.docType | Article | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Inorganic & Nuclear | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
| dc.subject.keywordPlus | ASYMMETRIC NUCLEOPHILIC-ADDITION | - |
| dc.subject.keywordPlus | ALKYLATION | - |
| dc.subject.keywordPlus | FUNGICIDES | - |
| dc.subject.keywordPlus | AUXILIARY | - |
| dc.subject.keywordPlus | SILYLOXY | - |
| dc.subject.keywordPlus | ETHER | - |
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Collections - 약학대학 > 약학부 > 1. Journal Articles
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