Detailed Information
Cited 0 time in 
Cited 89 time in 
Cited 89 time in
Metadata Downloads
The dual effects of interleukin-18 in tumor progression
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Park, Sunyoung | - |
| dc.contributor.author | Cheon, Soyoung | - |
| dc.contributor.author | Cho, Daeho | - |
| dc.date.available | 2021-02-22T15:02:01Z | - |
| dc.date.issued | 2007-10 | - |
| dc.identifier.issn | 1672-7681 | - |
| dc.identifier.issn | 2042-0226 | - |
| dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/14632 | - |
| dc.description.abstract | Interleukin-18 (IL-18) was discovered as an interferon-gamma-inducing factor and had a critical role in inflammatory and immune response. It stimulates natural killer (NK) and T cells and enhances Th1 immune response. These activated immune cells eliminate cancer cells and virus-infected cells effectively. However, IL-18 has also been found to promote tumor progression. Higher expression or secretion level of IL-18 is detected in various cancer cells in comparison with normal control, and IL-18 is able to induce angiogenesis, migration/metastasis, proliferation and immune escape. These dual effects and the mechanism of IL-18 need to be investigated further as it relates to cancer. | - |
| dc.format.extent | 7 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | CHIN SOCIETY IMMUNOLOGY | - |
| dc.title | The dual effects of interleukin-18 in tumor progression | - |
| dc.type | Article | - |
| dc.publisher.location | 캐나다 | - |
| dc.identifier.scopusid | 2-s2.0-39149101824 | - |
| dc.identifier.wosid | 000251044100002 | - |
| dc.identifier.bibliographicCitation | CELLULAR & MOLECULAR IMMUNOLOGY, v.4, no.5, pp 329 - 335 | - |
| dc.citation.title | CELLULAR & MOLECULAR IMMUNOLOGY | - |
| dc.citation.volume | 4 | - |
| dc.citation.number | 5 | - |
| dc.citation.startPage | 329 | - |
| dc.citation.endPage | 335 | - |
| dc.type.docType | Review | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Immunology | - |
| dc.relation.journalWebOfScienceCategory | Immunology | - |
| dc.subject.keywordPlus | ENDOTHELIAL GROWTH-FACTOR | - |
| dc.subject.keywordPlus | MURINE MELANOMA-CELLS | - |
| dc.subject.keywordPlus | FV/INTERLEUKIN-18 FUSION DNA | - |
| dc.subject.keywordPlus | 1-MEDIATED IMMUNE-RESPONSES | - |
| dc.subject.keywordPlus | CYTOTOXIC T-LYMPHOCYTES | - |
| dc.subject.keywordPlus | GAMMA-INDUCING FACTOR | - |
| dc.subject.keywordPlus | HUMAN GASTRIC-CANCER | - |
| dc.subject.keywordPlus | IFN-GAMMA | - |
| dc.subject.keywordPlus | INTERFERON-GAMMA | - |
| dc.subject.keywordPlus | INTRAMUSCULAR INJECTION | - |
| dc.subject.keywordAuthor | IL-18 | - |
| dc.subject.keywordAuthor | Th1 immune response | - |
| dc.subject.keywordAuthor | NK cytotoxicity | - |
| dc.subject.keywordAuthor | tumor progression | - |
| dc.subject.keywordAuthor | immune escape | - |
| dc.identifier.url | http://www.cmi.ustc.edu.cn/4/5/329.pdf | - |
- Files in This Item
- Go to Link
- Appears in
Collections - 대학 > 기초교양대학 > 기초교양학부 > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.