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Cell-specific activation of gemcitabine by endogenous H2S stimulation and tracking through simultaneous fluorescence turn-on
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Maiti, Mrinmoy | - |
| dc.contributor.author | Yoon, Shin A | - |
| dc.contributor.author | Cha, Yujin | - |
| dc.contributor.author | Athul, K. K. | - |
| dc.contributor.author | Bhuniya, Sankarprasad | - |
| dc.contributor.author | Lee, Min Hee | - |
| dc.date.accessioned | 2022-04-19T09:04:03Z | - |
| dc.date.available | 2022-04-19T09:04:03Z | - |
| dc.date.issued | 2021-09 | - |
| dc.identifier.issn | 1359-7345 | - |
| dc.identifier.issn | 1364-548X | - |
| dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/146373 | - |
| dc.description.abstract | The endogenous H2S-driven theranostic H2S-Gem has been invented. The theranostic prodrug H2S-Gem is selectively activated in cancer cells, releasing active gemcitabine with a simultaneous fluorescence turn-on. H2S-Gem selectively inhibited cancer cell growth compared to the mother chemotherapeutic gemcitabine. Overall, it is a unique protocol for tracking and transporting chemotherapeutic agents to tumor areas without the guidance of tumor-directive ligands. | - |
| dc.format.extent | 4 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | ROYAL SOC CHEMISTRY | - |
| dc.title | Cell-specific activation of gemcitabine by endogenous H2S stimulation and tracking through simultaneous fluorescence turn-on | - |
| dc.type | Article | - |
| dc.publisher.location | 영국 | - |
| dc.identifier.doi | 10.1039/d1cc00118c | - |
| dc.identifier.scopusid | 2-s2.0-85115649854 | - |
| dc.identifier.wosid | 000691876500001 | - |
| dc.identifier.bibliographicCitation | CHEMICAL COMMUNICATIONS, v.57, no.75, pp 9614 - 9617 | - |
| dc.citation.title | CHEMICAL COMMUNICATIONS | - |
| dc.citation.volume | 57 | - |
| dc.citation.number | 75 | - |
| dc.citation.startPage | 9614 | - |
| dc.citation.endPage | 9617 | - |
| dc.type.docType | Article | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
| dc.subject.keywordPlus | DRUG-DELIVERY | - |
| dc.subject.keywordPlus | HYDROGEN-SULFIDE | - |
| dc.subject.keywordPlus | THERANOSTIC PRODRUG | - |
| dc.subject.keywordPlus | CANCER-THERAPY | - |
| dc.subject.keywordPlus | PROBE | - |
| dc.identifier.url | https://pubs.rsc.org/en/content/articlelanding/2021/CC/D1CC00118C | - |
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