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A novel strategy to selectively detect Fe(III) in aqueous media driven by hydrolysis of a rhodamine 6G Schiff base
- Authors
- Lee, Min Hee; Van Giap, Thang; Kim, Sang Hoon; Lee, Young Hoon; Kang, Chulhun; Kim, Jong Seung
- Issue Date
- Mar-2010
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- CHEMICAL COMMUNICATIONS, v.46, no.9, pp 1407 - 1409
- Pages
- 3
- Journal Title
- CHEMICAL COMMUNICATIONS
- Volume
- 46
- Number
- 9
- Start Page
- 1407
- End Page
- 1409
- ISSN
- 1359-7345
1364-548X
- Abstract
- A rhodamine-based probe (FS1) was synthesized and its fluorescence properties and application to an iron-overloaded cell line demonstrated. FS1 underwent fluorogenic changes by the Fe(3+)-catalyzed reaction, even in the presence of other metal cations in vitro. Chemodosimeter FS1 demonstrated selective and sensitive detection of intracellular Fe(3+) in hepatocytes.
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