RpS3, a DNA repair endonuclease and ribosomal protein, is involved in apoptosis.
DC Field | Value | Language |
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dc.contributor.author | Jang, Chang Young | - |
dc.contributor.author | Lee, Jae Yung | - |
dc.contributor.author | Kim, Joon | - |
dc.date.accessioned | 2022-04-19T11:46:41Z | - |
dc.date.available | 2022-04-19T11:46:41Z | - |
dc.date.issued | 2004-02 | - |
dc.identifier.issn | 0014-5793 | - |
dc.identifier.issn | 1873-3468 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/148982 | - |
dc.description.abstract | It is known that mammalian rpS3 functions as a DNA repair endonuclease and ribosomal protein S3. It was also observed that several ribosomal proteins or DNA repair enzymes are related to apoptosis. We report here a third function of rpS3, induction of apoptosis. The localization of green fluorescent protein (GFP)-rpS3 is changed to the nuclear membrane when lymphocytic cells undergo rpS3-induced apoptosis. Transient expression of GFP-rpS3 activates caspase-8/caspase-3 and sensitizes cytokine-induced apoptosis. Deletion analysis reveals that the two functions of rpS3, DNA repair and apoptosis, use independent functional domains. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Federation of European Biochemical Societies | - |
dc.title | RpS3, a DNA repair endonuclease and ribosomal protein, is involved in apoptosis. | - |
dc.title.alternative | DNA repair endonuclease이고 ribosomal protein인 rpS3는 apoptosis에 관여한다. | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1016/S0014-5793(04)00074-2 | - |
dc.identifier.scopusid | 2-s2.0-1342265497 | - |
dc.identifier.wosid | 000189328900016 | - |
dc.identifier.bibliographicCitation | FEBS Letters - 직접입력, v.560, no.1-3, pp 81 - 85 | - |
dc.citation.title | FEBS Letters - 직접입력 | - |
dc.citation.volume | 560 | - |
dc.citation.number | 1-3 | - |
dc.citation.startPage | 81 | - |
dc.citation.endPage | 85 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0014579304000742 | - |
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