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Isolation and characterization of cDNA clone for human liver 10-formyltetrahydrofolate dehydrogenase

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dc.contributor.authorHong, M-
dc.contributor.authorLee, Y-
dc.contributor.authorKim, JW-
dc.contributor.authorLim, JS-
dc.contributor.authorChang, SY-
dc.contributor.authorSoo, K-
dc.contributor.authorPaik, SG-
dc.contributor.authorChoe, IS-
dc.date.accessioned2022-04-19T13:06:05Z-
dc.date.available2022-04-19T13:06:05Z-
dc.date.issued1999-03-
dc.identifier.issn1039-9712-
dc.identifier.urihttps://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/150168-
dc.description.abstractA cDNA clone encoding 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) was isolated from a human fetal liver cDNA library. It contained the open reading frame of 2,709 base pairs and predicted a protein comprising 902 amino acids with a calculated molecular weight of 98,700 Da. The deduced protein showed about 93.6 % homology (90.5 % identity, 3.1 % favored substitutions) when compared with rat 10-FTHFDH. The distribution of 10-FTHFDH transcript in various human tissues was studied by Northern blot analysis using poly(A(+)) RNAs from different tissues. The 10-FTHFDH transcript with an approximate size of 2.7 kb was mainly expressed in human kidney, skeletal muscle, and liver and rarely expressed in other tissues.-
dc.format.extent9-
dc.language영어-
dc.language.isoENG-
dc.publisherAcademic Press-
dc.titleIsolation and characterization of cDNA clone for human liver 10-formyltetrahydrofolate dehydrogenase-
dc.typeArticle-
dc.publisher.location미국-
dc.identifier.doi10.1080/15216549900201433-
dc.identifier.scopusid2-s2.0-0032943641-
dc.identifier.wosid000079512300007-
dc.identifier.bibliographicCitationBiochemistry and Molecular Biology International, v.47, no.3, pp 407 - 415-
dc.citation.titleBiochemistry and Molecular Biology International-
dc.citation.volume47-
dc.citation.number3-
dc.citation.startPage407-
dc.citation.endPage415-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.urlhttps://iubmb.onlinelibrary.wiley.com/doi/abs/10.1080/15216549900201433-
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