Isolation and characterization of cDNA clone for human liver 10-formyltetrahydrofolate dehydrogenase
DC Field | Value | Language |
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dc.contributor.author | Hong, M | - |
dc.contributor.author | Lee, Y | - |
dc.contributor.author | Kim, JW | - |
dc.contributor.author | Lim, JS | - |
dc.contributor.author | Chang, SY | - |
dc.contributor.author | Soo, K | - |
dc.contributor.author | Paik, SG | - |
dc.contributor.author | Choe, IS | - |
dc.date.accessioned | 2022-04-19T13:06:05Z | - |
dc.date.available | 2022-04-19T13:06:05Z | - |
dc.date.issued | 1999-03 | - |
dc.identifier.issn | 1039-9712 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/150168 | - |
dc.description.abstract | A cDNA clone encoding 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) was isolated from a human fetal liver cDNA library. It contained the open reading frame of 2,709 base pairs and predicted a protein comprising 902 amino acids with a calculated molecular weight of 98,700 Da. The deduced protein showed about 93.6 % homology (90.5 % identity, 3.1 % favored substitutions) when compared with rat 10-FTHFDH. The distribution of 10-FTHFDH transcript in various human tissues was studied by Northern blot analysis using poly(A(+)) RNAs from different tissues. The 10-FTHFDH transcript with an approximate size of 2.7 kb was mainly expressed in human kidney, skeletal muscle, and liver and rarely expressed in other tissues. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Academic Press | - |
dc.title | Isolation and characterization of cDNA clone for human liver 10-formyltetrahydrofolate dehydrogenase | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1080/15216549900201433 | - |
dc.identifier.scopusid | 2-s2.0-0032943641 | - |
dc.identifier.wosid | 000079512300007 | - |
dc.identifier.bibliographicCitation | Biochemistry and Molecular Biology International, v.47, no.3, pp 407 - 415 | - |
dc.citation.title | Biochemistry and Molecular Biology International | - |
dc.citation.volume | 47 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 407 | - |
dc.citation.endPage | 415 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.identifier.url | https://iubmb.onlinelibrary.wiley.com/doi/abs/10.1080/15216549900201433 | - |
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