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Total synthesis of sufentanil
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Shin, DY | - |
| dc.contributor.author | Ryu, JS | - |
| dc.contributor.author | Hyun, SS | - |
| dc.contributor.author | Park, HJ | - |
| dc.contributor.author | Jeon, RO | - |
| dc.contributor.author | Suh, YG | - |
| dc.date.accessioned | 2022-04-19T13:06:14Z | - |
| dc.date.available | 2022-04-19T13:06:14Z | - |
| dc.date.issued | 1999-08 | - |
| dc.identifier.issn | 0253-6269 | - |
| dc.identifier.issn | 1976-3786 | - |
| dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/150171 | - |
| dc.description.abstract | Sufentanil, a potent anilidopiperidine analgesic, was synthesized from a simple thiophenylethylamine via six step sequence. The key parts of this synthesis involved an efficient construction of thiophenylethylpiperidone by aminomethano desilylation-cyclization followed by Swern oxidation and a direct regioselective N-nucleophilic spiral epoxide cleavage with aniline promoted by Lewis acids. | - |
| dc.format.extent | 3 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | PHARMACEUTICAL SOC KOREA | - |
| dc.title | Total synthesis of sufentanil | - |
| dc.type | Article | - |
| dc.publisher.location | 대한민국 | - |
| dc.identifier.doi | 10.1007/BF02979064 | - |
| dc.identifier.scopusid | 2-s2.0-0033174964 | - |
| dc.identifier.wosid | 000082188700012 | - |
| dc.identifier.bibliographicCitation | ARCHIVES OF PHARMACAL RESEARCH, v.22, no.4, pp 398 - 400 | - |
| dc.citation.title | ARCHIVES OF PHARMACAL RESEARCH | - |
| dc.citation.volume | 22 | - |
| dc.citation.number | 4 | - |
| dc.citation.startPage | 398 | - |
| dc.citation.endPage | 400 | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
| dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
| dc.subject.keywordPlus | AMINOMETHANO DESILYLATION | - |
| dc.subject.keywordPlus | ALLYLSILANES | - |
| dc.subject.keywordAuthor | total synthesis | - |
| dc.subject.keywordAuthor | sufentanil | - |
| dc.subject.keywordAuthor | analgesics | - |
| dc.subject.keywordAuthor | piperidine | - |
| dc.subject.keywordAuthor | oxirane | - |
| dc.identifier.url | https://link.springer.com/article/10.1007/BF02979064 | - |
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