Mass spectrometry-based ginsenoside profiling: Recent applications, limitations, and perspectives
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Hyun Woo | - |
dc.contributor.author | Kim, Dae Hyun | - |
dc.contributor.author | Ryu, Byeol | - |
dc.contributor.author | Chung, You Jin | - |
dc.contributor.author | Lee, Kyungha | - |
dc.contributor.author | Kim, Young Chang | - |
dc.contributor.author | Lee, Jung Woo | - |
dc.contributor.author | Kim, Dong Hwi | - |
dc.contributor.author | Jang, Woojong | - |
dc.contributor.author | Cho, Woohyeon | - |
dc.contributor.author | Shim, Hyeonah | - |
dc.contributor.author | Sung, Sang Hyun | - |
dc.contributor.author | Yang, Tae-Jin | - |
dc.contributor.author | Kang, Kyo Bin | - |
dc.date.accessioned | 2024-04-30T07:00:45Z | - |
dc.date.available | 2024-04-30T07:00:45Z | - |
dc.date.issued | 2024-03 | - |
dc.identifier.issn | 1226-8453 | - |
dc.identifier.issn | 2093-4947 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/159927 | - |
dc.description.abstract | Ginseng, the roots of Panax species, is an important medicinal herb used as a tonic. As ginsenosides are key bioactive components of ginseng, holistic chemical profiling of them has provided many insights into understanding ginseng. Mass spectrometry has been a major methodology for profiling, which has been applied to realize numerous goals in ginseng research, such as the discrimination of different species, geographical origins, and ages, and the monitoring of processing and biotransformation. This review summarizes the various applications of ginsenoside profiling in ginseng research over the last three decades that have contributed to expanding our understanding of ginseng. However, we also note that most of the studies overlooked a crucial factor that influences the levels of ginsenosides: genetic variation. To highlight the effects of genetic variation on the chemical contents, we present our results of untargeted and targeted ginsenoside profiling of different genotypes cultivated under identical conditions, in addition to data regarding genome-level genetic diversity. Additionally, we analyze the other limitations of previous studies, such as imperfect variable control, deficient metadata, and lack of additional effort to validate causation. We conclude that the values of ginsenoside profiling studies can be enhanced by overcoming such limitations, as well as by integrating with other -omics techniques. © 2024 | - |
dc.format.extent | 14 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier B.V. | - |
dc.title | Mass spectrometry-based ginsenoside profiling: Recent applications, limitations, and perspectives | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.1016/j.jgr.2024.01.004 | - |
dc.identifier.scopusid | 2-s2.0-85183136188 | - |
dc.identifier.wosid | 001202749700001 | - |
dc.identifier.bibliographicCitation | Journal of Ginseng Research, v.48, no.2, pp 149 - 162 | - |
dc.citation.title | Journal of Ginseng Research | - |
dc.citation.volume | 48 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 149 | - |
dc.citation.endPage | 162 | - |
dc.type.docType | Review | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Integrative & Complementary Medicine | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Integrative & Complementary Medicine | - |
dc.subject.keywordPlus | NONTARGETED METABOLOMICS APPROACH | - |
dc.subject.keywordPlus | PANAX-QUINQUEFOLIUS-L. | - |
dc.subject.keywordPlus | MALONYL-GINSENOSIDES | - |
dc.subject.keywordPlus | WHITE GINSENG | - |
dc.subject.keywordPlus | COMPOUND K | - |
dc.subject.keywordPlus | RAT PLASMA | - |
dc.subject.keywordPlus | CHROMATOGRAPHY | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | DISCRIMINATION | - |
dc.subject.keywordPlus | NOTOGINSENG | - |
dc.subject.keywordAuthor | Chemical profiling | - |
dc.subject.keywordAuthor | Genetic variation | - |
dc.subject.keywordAuthor | Ginseng | - |
dc.subject.keywordAuthor | Ginsenoside | - |
dc.subject.keywordAuthor | Mass spectrometry | - |
dc.identifier.url | https://linkinghub.elsevier.com/retrieve/pii/S1226845324000058 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
Sookmyung Women's University. Cheongpa-ro 47-gil 100 (Cheongpa-dong 2ga), Yongsan-gu, Seoul, 04310, Korea02-710-9127
Copyright©Sookmyung Women's University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.