Comparison of lenograstim and filgrastim on haematological effects after autologous peripheral blood stem cell transplantation with high-dose chemotherapy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, IH | - |
dc.contributor.author | Park, SK | - |
dc.contributor.author | Suh, OK | - |
dc.contributor.author | Oh, JM | - |
dc.date.available | 2021-02-22T16:31:08Z | - |
dc.date.issued | 2003-00 | - |
dc.identifier.issn | 0300-7995 | - |
dc.identifier.issn | 1473-4877 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/16365 | - |
dc.description.abstract | Objective: To compare the efficacy of lenograstim and filgrastim on haematological recovery following an autologous peripheral blood stem cell transplantation (PBSCT) with high-dose chemotherapy. Methods: A retrospective case-controlled study. Results: Absolute neutrophil count (ANC) recovery above 0.5 x 10(9)/1 and white blood cell (WBC) recovery above 4 x 10(9)/1 for 3 consecutive days was achieved earlier with filgrastim than with lenograstim ((13.2 +/- 8.0 vs 19.0 +/- 10.0 days, p = 0.004), (16.9 +/- 9.7 vs 29.9 +/- 16.6 days, p = 0.001), respectively). The platelet recovery above 20 x 10(9)/1 was also achieved earlier with filgrastim than with lenograstim (19.5 +/- 11.6 vs 27.2 +/- 13.8 days, p = 0.006). Furthermore, filgrastim-treated patients received fewer days of granulocyte colony simulating factor (G-CSF) administration (12.5 +/- 7.0 vs 18.6 +/- 8.5 days, p = 0.001) and spent less time in hospital (23.7 +/- 10.9 vs 32.0 +/- 17.6 days, p = 0.009). Duration of antibiotic administration was also significantly shorter in the filgrastim group (13.6 +/- 7.6 vs 29.1 +/- 19.8 days, p = 0.001). Conclusion: In patients undergoing PBSCT following high-dose chemotherapy, filgrastim significantly reduced the duration of neutropenia, thrombocytopenia and days of G-CSF administration, and led to earlier hospital discharge compared with lenograstim. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | LIBRAPHARM | - |
dc.title | Comparison of lenograstim and filgrastim on haematological effects after autologous peripheral blood stem cell transplantation with high-dose chemotherapy | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1185/030079903125002531 | - |
dc.identifier.scopusid | 2-s2.0-0345276665 | - |
dc.identifier.wosid | 000186701000012 | - |
dc.identifier.bibliographicCitation | CURRENT MEDICAL RESEARCH AND OPINION, v.19, no.8, pp 753 - 759 | - |
dc.citation.title | CURRENT MEDICAL RESEARCH AND OPINION | - |
dc.citation.volume | 19 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 753 | - |
dc.citation.endPage | 759 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalResearchArea | Research & Experimental Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
dc.subject.keywordPlus | COLONY-STIMULATING FACTOR | - |
dc.subject.keywordPlus | BONE-MARROW TRANSPLANTATION | - |
dc.subject.keywordPlus | PROGENITOR CELLS | - |
dc.subject.keywordPlus | PLATELET RECOVERY | - |
dc.subject.keywordPlus | HODGKINS-DISEASE | - |
dc.subject.keywordPlus | RANDOMIZED TRIAL | - |
dc.subject.keywordPlus | GRANULOCYTE | - |
dc.subject.keywordPlus | LYMPHOMA | - |
dc.subject.keywordPlus | MALIGNANCIES | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordAuthor | filgrastim | - |
dc.subject.keywordAuthor | G-CSF | - |
dc.subject.keywordAuthor | lenograstim | - |
dc.subject.keywordAuthor | neutropenia | - |
dc.subject.keywordAuthor | PBSCT | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
Sookmyung Women's University. Cheongpa-ro 47-gil 100 (Cheongpa-dong 2ga), Yongsan-gu, Seoul, 04310, Korea02-710-9127
Copyright©Sookmyung Women's University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.