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Inhibition of Nitric Oxide Synthesis by 8-epi-xanthatin in Activated RAW 264.7 Cells

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dc.contributor.author이화진-
dc.contributor.author정연수-
dc.contributor.author류시용-
dc.contributor.author류재하-
dc.date.available2021-03-15T02:40:36Z-
dc.date.created2020-09-23-
dc.date.issued1998-10-
dc.identifier.issn0377-9556-
dc.identifier.urihttps://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/17535-
dc.description.abstractThe nitric oxide (NO) produced in large amounts by inducible nitric oxide synthase is known to be responsible for the vasodilation and hypotension observed in septic shock. We have found that 8-epi-xanthatin from Xanthium strumarium L. inhibited the production of NO in LPS-activated RAW 264.7 cells ($IC_{50}$ value was 1.5 ${\mu}$M). This activity was resulted from the suppressing of inducible nitric oxide synthase enzyme expression.-
dc.language한국어-
dc.language.isoko-
dc.publisher대한약학회-
dc.titleInhibition of Nitric Oxide Synthesis by 8-epi-xanthatin in Activated RAW 264.7 Cells-
dc.title.alternative활성화한 RAW 264.7 세포주에서 8-epi-xanthatin의 Nitric Oxide 생성저해-
dc.typeArticle-
dc.contributor.affiliatedAuthor류재하-
dc.identifier.bibliographicCitation약 학 회 지, v.42, no.5, pp.540 - 543-
dc.relation.isPartOf약 학 회 지-
dc.citation.title약 학 회 지-
dc.citation.volume42-
dc.citation.number5-
dc.citation.startPage540-
dc.citation.endPage543-
dc.type.rimsART-
dc.description.journalClass2-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassother-
dc.identifier.urlhttp://koreascience.kr/article/JAKO199815875840286.page-
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