Association of serum 25-hydroxyvitamin D and diabetes-related factors in Korean adults without diabetes: The Fifth Korea National Health and Nutrition Examination Survey 2010-2012
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Hyunah | - |
dc.contributor.author | Lee, Hyunyong | - |
dc.contributor.author | Yim, Hyeon Woo | - |
dc.contributor.author | Kim, Hun-Sung | - |
dc.date.available | 2021-02-22T09:46:05Z | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 1751-9918 | - |
dc.identifier.issn | 1878-0210 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/4688 | - |
dc.description.abstract | Aims: Vitamin D is associated with diabetes mellitus (DM) occurrence by affecting insulin secretion and resistance. However, variations exist due to differences in vitamin D sensitivity among individuals. We investigate the relationship between serum 25-hydroxyvitamin D [25(OH)D] status and various indices of DM in a Korean population without DM. Methods: Large-scaled population-based analysis was conducted from the Korea National Health and Nutrition Examination Survey data (2010-2012) were analyzed. Adult survey participants >20 years without diabetes (n=15,169) were included. Results: The mean 25(OH)D levels were lower in females, subjects aged 20-39 years, and subjects with body mass index <21.1 kg/m(2) and less physical activity (p <0.001). Further, the mean 25(OH)D levels tended to be lower in subjects with FBG >126 mg/dL. After adjustment for potential confounders, 25(OH)D was not correlated with FBG (p =0.925) or HbA1c (p =0.336); however, fasting insulin (beta= -0.072, p =0.011) and homeostasis model assessment of (beta-cell function (beta= -0.007, p <0.001) showed significant negative correlations with 25(OH)D levels. Conclusion: Although 25(OH)D status was not significantly associated with FBG or HbA1c, low 25(OH)D levels were associated with compensative insulin increase and ongoing increase in insulin resistance. Thus, vitamin D deficiency is assumed to influence DM occurrence. (C) 2017 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.title | Association of serum 25-hydroxyvitamin D and diabetes-related factors in Korean adults without diabetes: The Fifth Korea National Health and Nutrition Examination Survey 2010-2012 | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1016/j.pcd.2017.07.002 | - |
dc.identifier.scopusid | 2-s2.0-85026513071 | - |
dc.identifier.wosid | 000423008800007 | - |
dc.identifier.bibliographicCitation | PRIMARY CARE DIABETES, v.12, no.1, pp 59 - 65 | - |
dc.citation.title | PRIMARY CARE DIABETES | - |
dc.citation.volume | 12 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 59 | - |
dc.citation.endPage | 65 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Primary Health Care | - |
dc.subject.keywordPlus | VITAMIN-D SUPPLEMENTATION | - |
dc.subject.keywordPlus | INSULIN-RESISTANCE | - |
dc.subject.keywordPlus | METABOLIC SYNDROME | - |
dc.subject.keywordPlus | D DEFICIENCY | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | CALCIUM | - |
dc.subject.keywordPlus | GLUCOSE | - |
dc.subject.keywordPlus | POPULATION | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | TRENDS | - |
dc.subject.keywordAuthor | Diabetes mellitus | - |
dc.subject.keywordAuthor | Vitamin D deficiency | - |
dc.subject.keywordAuthor | 25-hydroxyvitamin D | - |
dc.subject.keywordAuthor | Insulin resistance | - |
dc.identifier.url | https://www.primary-care-diabetes.com/article/S1751-9918(17)30114-6/fulltext | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
Sookmyung Women's University. Cheongpa-ro 47-gil 100 (Cheongpa-dong 2ga), Yongsan-gu, Seoul, 04310, Korea02-710-9127
Copyright©Sookmyung Women's University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.