Rosacea: Molecular Mechanisms and Management of a Chronic Cutaneous Inflammatory Condition
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Woo, Yu Ri | - |
dc.contributor.author | Lim, Ji Hong | - |
dc.contributor.author | Cho, Dae Ho | - |
dc.contributor.author | Park, Hyun Jeong | - |
dc.date.available | 2021-02-22T11:24:36Z | - |
dc.date.issued | 2016-09 | - |
dc.identifier.issn | 1661-6596 | - |
dc.identifier.issn | 1422-0067 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/9443 | - |
dc.description.abstract | Rosacea is a chronic cutaneous inflammatory disease that affects the facial skin. Clinically, rosacea can be categorized into papulopustular, erythematotelangiectatic, ocular, and phymatous rosacea. However, the phenotypic presentations of rosacea are more heterogeneous. Although the pathophysiology of rosacea remains to be elucidated, immunologic alterations and neurovascular dysregulation are thought to have important roles in initiating and strengthening the clinical manifestations of rosacea. In this article, we present the possible molecular mechanisms of rosacea based on recent laboratory and clinical studies. We describe the genetic predisposition for rosacea along with its associated diseases, triggering factors, and suggested management options in detail based on the underlying molecular biology. Understanding the molecular pathomechanisms of rosacea will likely aid toward better comprehending its complex pathogenesis. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI | - |
dc.title | Rosacea: Molecular Mechanisms and Management of a Chronic Cutaneous Inflammatory Condition | - |
dc.type | Article | - |
dc.publisher.location | 스위스 | - |
dc.identifier.doi | 10.3390/ijms17091562 | - |
dc.identifier.scopusid | 2-s2.0-84988484308 | - |
dc.identifier.wosid | 000385525500179 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.17, no.9 | - |
dc.citation.title | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.citation.volume | 17 | - |
dc.citation.number | 9 | - |
dc.type.docType | Review | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.subject.keywordPlus | DIFFERENTIATION REGULATOR 1 | - |
dc.subject.keywordPlus | SERINE-PROTEASE ACTIVITY | - |
dc.subject.keywordPlus | INTESTINAL BACTERIAL OVERGROWTH | - |
dc.subject.keywordPlus | HELICOBACTER-PYLORI INFECTION | - |
dc.subject.keywordPlus | FREE OXYGEN RADICALS | - |
dc.subject.keywordPlus | SKIN BLOOD-FLOW | - |
dc.subject.keywordPlus | VITAMIN-D | - |
dc.subject.keywordPlus | DEMODEX-FOLLICULORUM | - |
dc.subject.keywordPlus | NITRIC-OXIDE | - |
dc.subject.keywordPlus | STAPHYLOCOCCUS-EPIDERMIDIS | - |
dc.subject.keywordAuthor | rosacea | - |
dc.subject.keywordAuthor | genetic | - |
dc.subject.keywordAuthor | triggering factor | - |
dc.subject.keywordAuthor | immune defect | - |
dc.subject.keywordAuthor | inflammation | - |
dc.subject.keywordAuthor | neurovascular dysregulation | - |
dc.identifier.url | https://www.mdpi.com/1422-0067/17/9/1562 | - |
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