Evaluation of enteral formulas for nutrition, health, and quality of life among stroke patients
- Authors
- Kang, Yunkyeong; Lee, Ho-Sun; Paik, Nam-Jong; Kim, Woo-Sub; Yang, Mihi
- Issue Date
- Oct-2010
- Publisher
- KOREAN NUTRITION SOC
- Keywords
- Stroke; enteral nutrition; sense of competence questionnaire; biomarkers; malondialdehyde
- Citation
- NUTRITION RESEARCH AND PRACTICE, v.4, no.5, pp 393 - 399
- Pages
- 7
- Journal Title
- NUTRITION RESEARCH AND PRACTICE
- Volume
- 4
- Number
- 5
- Start Page
- 393
- End Page
- 399
- URI
- https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/13117
- DOI
- 10.4162/nrp.2010.4.5.393
- ISSN
- 1976-1457
2005-6168
- Abstract
- Enteral nutritional support has been used via tube feeding for dysphagic stroke patients. We performed long and short term trials to evaluate the effects of commercial enteral nutritional supports on nutrition and health in stroke patients (mRS = 3 similar to 5) and quality of life in their caregivers. For a long term study, we recruited chronic (>= 1 yrs) stroke patients (n = 6) and administered them 6 cans/day (1,200 kcal) of the commercial enteral formula N for 6 months according to IRB-approved protocol. We collected peripheral blood at 0, 2, 4 and 6 months. For a short term study, we recruited acute 3 months) stroke patients (n = 12) and randomly administered them two different commercial enteral formulas, N or J, for 2 weeks. We collected their blood at 0, 4, 7 and 14 day of the administration. Blood samples were analyzed to quantify 19 health and nutritional biomarkers and an oxidative stress biomarker, malondialdehyde (MDA). In order to evaluate quality of life, we also obtained the sense of competence questionnaire (SCQ) from all caregivers at 'before' and 'after trials'. As results, the enteral formula, N, improved hemoglobin and hematocrit levels in the long term trial and maintained most of biomarkers within normal ranges. The SCQ levels of caregivers were improved in the long term treatment (P < 0.05). In a case of the short term study, both of enteral formulas were helpful to maintain nutritional status of the patients. In addition, MDA levels were decreased in the acute patients following formula consumption (0.05 < P < 0.1). Most of health and nutrition outcomes were not different, even though there is a big difference in price of the two products. Thus, we evaluate the formula N has equal nutritional efficacy compared to the formula J. In addition, long term use of enteral formula N can be useful to health and nutrition of stroke patients, and the quality of life for their caregivers.
- Files in This Item
-
Go to Link
- Appears in
Collections - 약학대학 > 약학부 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/13117)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.