Detailed Information
Cited 0 time in 
Cited 10 time in 
Cited 10 time in
Metadata Downloads
Nano-biopower supplies for biomolecular motors: the use of metabolic pathway-based fuel generating systems in microfluidic devices
- Authors
- Wasylycia, Joshua R.; Sapelnikova, Svetlana; Jeong, Hyuk; Dragoljic, Jelena; Marcus, Sandra L.; Harrison, D. Jed
- Issue Date
- Apr-2008
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- LAB ON A CHIP, v.8, no.6, pp 979 - 982
- Pages
- 4
- Journal Title
- LAB ON A CHIP
- Volume
- 8
- Number
- 6
- Start Page
- 979
- End Page
- 982
- ISSN
- 1473-0197
1473-0189
- Abstract
- We report fuel generation systems for molecular motors based on pyruvate kinase, or for the first time, mitochondria, implemented within microfluidic devices. Intact organelles acted as bio-nanopower supplies for molecular motors, using isolated mitochondria to convert chemical energy from succinate to ATP, harnessing nature's enzymatic transformation cascades directly. Motors were activated essentially equally by ATP produced by pyruvate kinase, mitochondria, or direct addition of ATP.
- Files in This Item
- Go to Link
- Appears in
Collections - 이과대학 > 화학과 > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.