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Jubanines F-J, cyclopeptide alkaloids from the roots of Ziziphus jujuba
- Authors
- Kang, Kyo Bin; Ming, Gao; Kim, Geum Jin; Ha, Thi-Kim-Quy; Choi, Hyukjae; Oh, Won Keun; Sung, Sang Hyun
- Issue Date
- Nov-2015
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Citation
- PHYTOCHEMISTRY, v.119, pp 90 - 95
- Pages
- 6
- Journal Title
- PHYTOCHEMISTRY
- Volume
- 119
- Start Page
- 90
- End Page
- 95
- ISSN
- 0031-9422
- Abstract
- Five Ib-type cyclopeptide alkaloids, jubanines F-J (1-5), and three known compounds, nummularine B (6), daechuine-S3 (7), and mucronine K (8) were isolated from the roots of Ziziphus jujuba. Their structures were fully characterized by spectroscopic analyses in combination with chemical derivatization. Compounds 1-3, and 6 were evaluated for their antiviral activity against the porcine epidemic diarrhea virus (PEDV). Compounds 2, 3, and 6 showed potent inhibitory effects on PEDV replication. (C) 2015 Elsevier Ltd. All rights reserved.
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