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Anti-angiogenic activity of the methanol extract and its fractions of Ulmus davidiana var. japonica
- Authors
- Jung, Hyun-Joo; Jeon, Hye-Jin; Lim, Eun-Ju; Ahn, Eun-Kyoung; Song, Yun Seon; Lee, Sanghyun; Shin, Kuk Hyun; Lim, Chang-Jin; Park, Eun-Hee
- Issue Date
- Jun-2007
- Publisher
- ELSEVIER IRELAND LTD
- Keywords
- Ulmus davidiana var. japonica; angiogenesis; anti-angiogenic; chorioallantoic membrane; Ulmaceae
- Citation
- JOURNAL OF ETHNOPHARMACOLOGY, v.112, no.2, pp 406 - 409
- Pages
- 4
- Journal Title
- JOURNAL OF ETHNOPHARMACOLOGY
- Volume
- 112
- Number
- 2
- Start Page
- 406
- End Page
- 409
- ISSN
- 0378-8741
- Abstract
- This study aimed to elucidate anti-angiogenic activity of Ulmus davidiana var. japonica that has been widely used in folk medicine. The methanol extract (UDE) of Uhnus davidiana var. japonica concentration-dependently displayed a strong inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. The n-butanol fraction of UDE and subsequent 30% MeOH subtraction were identified to be most responsible for the anti-angiogenic activity. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
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