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Anti-angiogenic activity of the methanol extract and its fractions of Ulmus davidiana var. japonica

Authors
Jung, Hyun-JooJeon, Hye-JinLim, Eun-JuAhn, Eun-KyoungSong, Yun SeonLee, SanghyunShin, Kuk HyunLim, Chang-JinPark, Eun-Hee
Issue Date
13-Jun-2007
Publisher
ELSEVIER IRELAND LTD
Keywords
Ulmus davidiana var. japonica; angiogenesis; anti-angiogenic; chorioallantoic membrane; Ulmaceae
Citation
JOURNAL OF ETHNOPHARMACOLOGY, v.112, no.2, pp.406 - 409
Journal Title
JOURNAL OF ETHNOPHARMACOLOGY
Volume
112
Number
2
Start Page
406
End Page
409
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/14677
DOI
10.1016/j.jep.2007.03.006
ISSN
0378-8741
Abstract
This study aimed to elucidate anti-angiogenic activity of Ulmus davidiana var. japonica that has been widely used in folk medicine. The methanol extract (UDE) of Uhnus davidiana var. japonica concentration-dependently displayed a strong inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. The n-butanol fraction of UDE and subsequent 30% MeOH subtraction were identified to be most responsible for the anti-angiogenic activity. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
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