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HPLC-UV를 이용한 천마의 Gastrodin과 Gastrodigenin의 동시분석법 확립Simultaneous determination of gastrodin and gastrodigenin in gastrodia elata by HPLC-UV
- Other Titles
- Simultaneous determination of gastrodin and gastrodigenin in gastrodia elata by HPLC-UV
- Authors
- Kang K.B.; Jun J.B.; Yoo G.; Kwon E.; Yun J.-W.; Kang B.-C.; Kim S.H.; Sung S.H.; Jang Y.P.; Yang H.
- Issue Date
- Sep-2017
- Publisher
- 한국생약학회
- Keywords
- HPLC analysis; Gastrodia elata; Gastrodin; Gastrodigenin; Method validation
- Citation
- 생약학회지, v.48, no.3, pp 232 - 236
- Pages
- 5
- Journal Title
- 생약학회지
- Volume
- 48
- Number
- 3
- Start Page
- 232
- End Page
- 236
- ISSN
- 02533073
2288-9299
- Abstract
- Gastrodia elata has been widely used as a traditional medicinal herb. However, in Korean Pharmacopeia, neither a marker constituent nor an analytical procedure for G. elata has been established. In this study, we suggest gastrodin and gastrodigenin as marker constituents of G. elata, and propose an analytical procedure for simultaneous quantification of these constituents by high-performance liquid chromatography-ultraviolet spectroscopy (HPLC-UV). The analytical method was validated for its linearity, precision, accuracy, and specificity. Based on the validated method, gastrodin and gastrodigenin in 14 commercial G. elata samples were quantified.
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