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Ginsenoside Rg5, A genuine dammarane glycoside from Korean red ginseng
- Authors
- Kim, Shin Il; Park, Jeong Hill; Park, Jong Dae; Ryu, Jae Ha; Lee, You Hui; Park, Jae-Hyun; Kim, Tae-Hee; Kim, Jong Moon; Baek, Nam-In
- Issue Date
- Dec-1996
- Publisher
- 대한약학회
- Citation
- Archives of Pharmacal Research, v.19, no.6, pp 551 - 553
- Pages
- 3
- Journal Title
- Archives of Pharmacal Research
- Volume
- 19
- Number
- 6
- Start Page
- 551
- End Page
- 553
- ISSN
- 0253-6269
1976-3786
- Abstract
- A genuine dammarane glycoside, named ginsenoside Rg5, has been isolated by repeated column chromatography and preparative HPLC from the MeOH extract of Korean red ginseng (Panax ginseng C.A. Meyer). The chemical structure of ginsenoside Rg5 was determined as 3-O-[β-D-glucopyranosyl (1→2)-β-D-glucopyranosyl] dammar-20(22),24-diene-3β,12β-diol by spectral and chemical methods. The stereostructure of a double bond at C-20(22) of ginsenoside Rg5 was characterized as (E) from the chemical shift of C-21 in the13C-NMR and a NOESY experiment in the1H-NMR.
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