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PPAR의 리간드로서 새로운 요소 유도체의 분자설계 및 합성Design and Synthesis of Novel Urea Analog as a PPAR ligand
- Other Titles
- Design and Synthesis of Novel Urea Analog as a PPAR ligand
- Issue Date
- Feb-2006
- Publisher
- 숙명여자대학교 약학연구소
- Citation
- 약학논문집-숙명여자대학교, v.23, pp 50 - 54
- Journal Title
- 약학논문집-숙명여자대학교
- Volume
- 23
- Start Page
- 50
- End Page
- 54
- ISSN
- 1225-3723
- Abstract
- PPAR is one of the significant drug targets and activation of PPAR □ by several thiazolidinedione derivatives is well established. Herein bioisosteric replacement of thiazolidinedione to urea was carried out. Non-thiazolidinedione derivatives, [4-(2-carbazol-9-ylethoxy)phenyl]ureas (5, 6) were designed and synthesized to obtain novel PPAR activators.
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Collections - 약학대학 > 약학부 > 1. Journal Articles
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