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Design and Synthesis of (+/-)-3-Deoxygericudranin A as an Antitumour Agent항암제로서의 (+/-)-3-데옥시제리쿠드라닌 A의 설계 및 합성
- Other Titles
- 항암제로서의 (+/-)-3-데옥시제리쿠드라닌 A의 설계 및 합성
- Issue Date
- Jan-1997
- Publisher
- 대한약학회
- Citation
- 약 학 회 지, v.41, no.1, pp 14 - 17
- Pages
- 4
- Journal Title
- 약 학 회 지
- Volume
- 41
- Number
- 1
- Start Page
- 14
- End Page
- 17
- ISSN
- 0377-9556
2383-9457
- Abstract
- (+/-)-3 Deoxygericudranin A was designed and synthesized for the development of novel antitumour agent and for the elucidation of the effect of 3-hydroxyl group in gericudranin A on antitumour activity. 2,4.6-Trihydroxyacetophenone was converted to 3-deoxygericudranin A in 5 steps via sequential protection, aldol condensation, Michael tvpe-cyclization, regioselective, C-benzylation and deprotection.
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Collections - 약학대학 > 약학부 > 1. Journal Articles
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