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Formation of Methyl 2 3 -Epoxy-23-hydroxyurs-12-en-28-oate from Asiaticoside and its reductive epoxide ring opening reaction

Authors
주상섭임두연서성기남태규박형근김희두김창민이민희백형근이민정정영훈
Issue Date
Oct-1998
Publisher
대한약학회
Citation
약 학 회 지, v.42, no.5, pp 500 - 506
Pages
7
Journal Title
약 학 회 지
Volume
42
Number
5
Start Page
500
End Page
506
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/159206
ISSN
0377-9556
2383-9457
Abstract
Steroidal 2 β , 3 β --epoxy compound was prepared from asiaticoside via six steps and reduced regioselectively with lithium aluminum hydride. Epoxide ring opening furnished 9 as a sole product at reflux condition through axial hydride attack at C-3.
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