국내 체중 감량 약물 사용 현황 : 자발적으로 온라인에 게시한 처방전 분석open accessThe Use of Weight Loss Medication in Korea: An Analysis of Prescriptions Voluntarily Posted Online
- Other Titles
- The Use of Weight Loss Medication in Korea: An Analysis of Prescriptions Voluntarily Posted Online
- Authors
- 이소영; 이지은; 김미리; 정은아; 조 은
- Issue Date
- Nov-2023
- Publisher
- 건강보험심사평가원
- Keywords
- Obesity; Off-label use; Polypharmacy; Prescription drugs; Weight loss
- Citation
- HIRA Research, v.3, no.2, pp 182 - 195
- Pages
- 14
- Journal Title
- HIRA Research
- Volume
- 3
- Number
- 2
- Start Page
- 182
- End Page
- 195
- URI
- https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/159670
- DOI
- 10.52937/hira.23.3.2.e6
- ISSN
- 2765-6764
2765-7353
- Abstract
- Background: Multiple medications have been used for weight loss (WL); however, research on the regimens of WL treatment in Korea have been limited. This study aimed to characterize the medications prescribed for WL in real-world settings.
Methods: The study sample comprised WL prescriptions (Rxs) shared via a portal site for 1 year (from June 2022 to May 2023). WL drugs were classified into four categories: (1) on-label WL drugs; (2) off-label WL drugs; (3) medication-induced symptom management drugs; (4) dietary supplements and others. We calculated prescribing occurrence rates for each category and drugs. Further, we investigated the usage of off-label and psychotropic drug prescribing.
Results: The study sample included 66 Rxs consisting of 63 active ingredients. The average number of medications per Rxs was seven (range, 1–13). Acetaminophen/caffeine/(pseudo)ephedrine (59.1%) and topiramate (54.5%) were the most commonly used medicines. The most frequently prescribed drug regimen involved a combination of on-label WL, off-label WL, and medication-induced symptom management drugs.
Conclusion: Psychotropic appetite suppressants have been prescribed with unapproved WL drugs or psychotropic anti-anxiety/hypnotics. Further research is needed to provide evidence on drug combinations to ensure the safety of WL treatments.
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