Vitamin D and Colorectal Cancer Prevention: A Review of Epidemiologic Studies
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Jung Eun | - |
dc.date.available | 2021-02-22T10:56:17Z | - |
dc.date.issued | 2013-03 | - |
dc.identifier.issn | 2161-3311 | - |
dc.identifier.issn | 2161-3311 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/6431 | - |
dc.description.abstract | Vitamin D is hypothesized to prevent cancer development, and its potential anticarcinogenic effect against colorectal cancer has been explored in epidemiologic studies. Epidemiologic studies found that a low circulating level of 25-hydroxyvitamin D was associated with higher risk of colorectal cancer, whereas the association for vitamin D intake has not been as clear as for circulating vitamin D levels. A large intervention study on vitamin D supplementation and colorectal cancer did not show a protective benefit against colorectal cancer development, but several possible explanations remain open. Genetic polymorphisms in the pathway of vitamin D metabolism also have drawn attention, and single polymorphism studies and Genome Wide Association Studies (GWAS) have been conducted. Given a relatively high prevalence of vitamin D insufficiency among industrialized populations, further research on the optimal dose and duration of vitamin D supplementation, interaction with other nutrients or genes, and the appropriate timing of vitamin D interventions is warranted. © 2012 Springer Science+Business Media New York. | - |
dc.format.extent | 10 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Current Science Inc. | - |
dc.title | Vitamin D and Colorectal Cancer Prevention: A Review of Epidemiologic Studies | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1007/s13668-012-0037-8 | - |
dc.identifier.scopusid | 2-s2.0-84985000785 | - |
dc.identifier.bibliographicCitation | Current Nutrition Reports, v.2, no.1, pp 27 - 36 | - |
dc.citation.title | Current Nutrition Reports | - |
dc.citation.volume | 2 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 27 | - |
dc.citation.endPage | 36 | - |
dc.type.docType | Review | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | 25 hydroxyvitamin D | - |
dc.subject.keywordPlus | calcium | - |
dc.subject.keywordPlus | cytochrome P450 | - |
dc.subject.keywordPlus | placebo | - |
dc.subject.keywordPlus | vitamin D | - |
dc.subject.keywordPlus | cancer risk | - |
dc.subject.keywordPlus | carcinogenesis | - |
dc.subject.keywordPlus | colorectal adenoma | - |
dc.subject.keywordPlus | colorectal cancer | - |
dc.subject.keywordPlus | disease association | - |
dc.subject.keywordPlus | drug dose increase | - |
dc.subject.keywordPlus | genetic polymorphism | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | meta analysis (topic) | - |
dc.subject.keywordPlus | nonhuman | - |
dc.subject.keywordPlus | priority journal | - |
dc.subject.keywordPlus | randomized controlled trial (topic) | - |
dc.subject.keywordPlus | recommended drug dose | - |
dc.subject.keywordPlus | review | - |
dc.subject.keywordPlus | solar radiation | - |
dc.subject.keywordPlus | systematic review (topic) | - |
dc.subject.keywordPlus | vitamin blood level | - |
dc.subject.keywordPlus | vitamin D metabolism | - |
dc.subject.keywordPlus | vitamin intake | - |
dc.subject.keywordAuthor | 25-hydroxyvitamin D | - |
dc.subject.keywordAuthor | Colorectal adenoma | - |
dc.subject.keywordAuthor | Colorectal cancer | - |
dc.subject.keywordAuthor | Epidemiology | - |
dc.subject.keywordAuthor | Vitamin D | - |
dc.identifier.url | https://link.springer.com/article/10.1007%2Fs13668-012-0037-8 | - |
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