Association of serum and hair antioxidant minerals with an oxidative stress marker in relation with characteristics of healthy adults: a cross-sectional study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kang, Yoo-Ree | - |
dc.contributor.author | Sung, Mi-Kyung | - |
dc.contributor.author | Baik, Hyun-Wook | - |
dc.contributor.author | Choi, Mi-Kyeong | - |
dc.date.accessioned | 2024-03-22T05:31:26Z | - |
dc.date.available | 2024-03-22T05:31:26Z | - |
dc.date.issued | 2024-02 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/159763 | - |
dc.description.abstract | Excess oxidative stress generated in the body causes various types of cellular damage, including DNA damage. Certain trace minerals act as antioxidants by functioning as cofactors for antioxidant enzymes. This study was conducted to evaluate the serum and hair concentrations of major antioxidant trace minerals (zinc, manganese, selenium, and chromium) and to determine the association between the oxidative stress marker urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) and serum or hair antioxidant trace mineral concentrations, according to the general characteristics of healthy adults. Study participants were selected after screening, and 108 participants aged 19-69 years were finally included. Serum and hair trace mineral concentrations were analyzed using inductively coupled plasma mass spectrometry, and urine 8-OHdG levels were quantified using an ELISA kit. Results showed that urinary 8-OHdG levels were significantly higher in exercisers than in those who did not exercise. Correlation analysis revealed that urinary 8-OHdG was negatively correlated with hair zinc in participants over 60 years of age and with poor health status, and positively correlated with hair chromium in participants with irregular dietary habits. In conclusion, these results suggest that urinary 8-OHdG is particularly correlated with hair zinc and chromium levels. Additional large-scale epidemiological studies are needed to generally confirm these findings. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | NATURE PORTFOLIO | - |
dc.title | Association of serum and hair antioxidant minerals with an oxidative stress marker in relation with characteristics of healthy adults: a cross-sectional study | - |
dc.type | Article | - |
dc.publisher.location | 독일 | - |
dc.identifier.doi | 10.1038/s41598-024-53725-6 | - |
dc.identifier.scopusid | 2-s2.0-85184738342 | - |
dc.identifier.wosid | 001159201000101 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, v.14, no.1 | - |
dc.citation.title | SCIENTIFIC REPORTS | - |
dc.citation.volume | 14 | - |
dc.citation.number | 1 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | CHROMIUM SUPPLEMENTATION | - |
dc.subject.keywordPlus | TRACE-ELEMENTS | - |
dc.subject.keywordPlus | ZINC | - |
dc.subject.keywordPlus | BIOMARKER | - |
dc.subject.keywordAuthor | Oxidative stress | - |
dc.subject.keywordAuthor | Antioxidants | - |
dc.subject.keywordAuthor | Trace elements | - |
dc.subject.keywordAuthor | 8-hydroxy-2 '-deoxyguanosine (8-OHdG) | - |
dc.subject.keywordAuthor | Zinc | - |
dc.subject.keywordAuthor | Chromium | - |
dc.identifier.url | https://www.nature.com/articles/s41598-024-53725-6 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
Sookmyung Women's University. Cheongpa-ro 47-gil 100 (Cheongpa-dong 2ga), Yongsan-gu, Seoul, 04310, Korea02-710-9127
Copyright©Sookmyung Women's University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.