수수 물 추출물이 마우스 면역세포와 항체 생성능에 미치는 영향
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경옥 | - |
dc.contributor.author | 김현숙 | - |
dc.contributor.author | 류혜숙 | - |
dc.date.available | 2021-02-22T11:17:44Z | - |
dc.date.issued | 2006-02 | - |
dc.identifier.issn | 1225-9861 | - |
dc.identifier.issn | 2383-966X | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/8910 | - |
dc.description.abstract | This study was performed to evaluate the effect of Sorghum bicolor L. Moench(Sorghum, su-su) extracts on mouse immune cell activation. As ex vivo experiment, different concentrations(0, 50, 500mg/kg B.W.) of Sorghum bicolor L. Moench water extracts were orally administrated into mouse every other day for four weeks. The proliferation of mouse splenocytes, the number of plaque forming cells(PFC) and the cytokine IL-1β production by activated macrophage were used as indices for immunocompetence. Splenocyte proliferation was enhanced in mouse orally administrated with 50mg/kg B.W./day concentration compared to that of control group. Especially, the highest proliferation of spleoncyte was seen in the mouse orally administrated at the concentration of 50mg/kg B.W./day. The number of plaque forming cells(PFC) to SRBC were significantly enhanced when compared with control group. Also, the mouse of Sorghum bicolor L. Moench water extracts 50mg/kg B.W./day supplementation group with LPS stimulation enhanced level of IL-1β cytokine production. This study suggest that supplementation of Sorghum bicolor L. Moench water extracts may enhance the immune function by regulating the splenocytes proliferation, increasing the number of PFC and enhancing the cytokine production by activated macrophage. | - |
dc.format.extent | 7 | - |
dc.language | 한국어 | - |
dc.language.iso | KOR | - |
dc.publisher | 대한영양사협회 | - |
dc.title | 수수 물 추출물이 마우스 면역세포와 항체 생성능에 미치는 영향 | - |
dc.title.alternative | Effect of Sorghum bicolor L. Moench(Sorghum, su-su) Water Extracts on Mouse Immune Cell Activation | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.bibliographicCitation | 대한영양사협회 학술지, v.12, no.1, pp 82 - 88 | - |
dc.citation.title | 대한영양사협회 학술지 | - |
dc.citation.volume | 12 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 82 | - |
dc.citation.endPage | 88 | - |
dc.identifier.kciid | ART001158853 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Sorghum bicolor L. Moench | - |
dc.subject.keywordAuthor | Immune Function | - |
dc.subject.keywordAuthor | Spleen | - |
dc.subject.keywordAuthor | PFC | - |
dc.subject.keywordAuthor | IL-1β | - |
dc.identifier.url | http://kiss.kstudy.com/thesis/thesis-view.asp?key=2500591 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
Sookmyung Women's University. Cheongpa-ro 47-gil 100 (Cheongpa-dong 2ga), Yongsan-gu, Seoul, 04310, Korea02-710-9127
Copyright©Sookmyung Women's University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.