Effects of Bifidus Enhancer Yogurt on Relief from Loperamide-induced Constipation
- Authors
- Choi, Jin-Hee; Jeong, Seung-Hwan; Cho, Young-Hoon; Cho, Yun-Kyung; Choi, Hae-Yeon; Kim, Sun-Im
- Issue Date
- Feb-2012
- Publisher
- KOREAN SOC FOOD SCIENCE ANIMAL RESOURCES
- Keywords
- bifidus-enhancer yogurt; rice-DDGS; constipation; loperamide
- Citation
- KOREAN JOURNAL FOR FOOD SCIENCE OF ANIMAL RESOURCES, v.32, no.1, pp 24 - 30
- Pages
- 7
- Journal Title
- KOREAN JOURNAL FOR FOOD SCIENCE OF ANIMAL RESOURCES
- Volume
- 32
- Number
- 1
- Start Page
- 24
- End Page
- 30
- URI
- https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/11991
- DOI
- 10.5851/kosfa.2012.32.1.24
- ISSN
- 1225-8563
- Abstract
- This study investigated the effects of bifidus enhancer yogurt (BEY) on loperamide-induced constipation in rats. The bifidus enhancer, made of rice-DDGS (Dried Distillers Grains with Solubles), improved proliferation of bifidobacteria (BB-12). Male SD rats were induced with constipation using loperamide and were then used to test the effectiveness of BEY in relieving constipation. The rats were divided into four groups: normal group (NOR), loperamide-treated group (LOP), bifidus enhancer yogurt and loperamide-treated group (L-BEY), and commercial yogurt and loperamide-treated group (L-CY). Treatment of loperamide reduced the wet weight and water content of fecal pellets, but increased the number of fecal pellets in the distal colon. Meanwhile, the fecal weight of the L-BEY group showed an increase of 43% and 23% versus the LOP and L-CY group, respectively. Also, the fecal water content in the L-BEY group was 14.5% and 6.8% higher than that in the LOP and L-CY group, respectively. In addition, the L-BEY group had the fewest fecal pellets in the distal colon. In the serum lipid parameters, the LOP group had a HDL/total cholesterol ratio that was 43% lower than the NOR group, but the L-BEY group had 27% lower than NOR group. These results suggest that bifidus enhancer yogurt has superior effects when it comes to relieving loperamide-induced constipation in rats.
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Collections - 생활과학대학 > 식품영양학과 > 1. Journal Articles
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