Cancer Research publishes original studies, reviews, and opinion pieces offering significance and broad impact to a diverse audience. Cancer Research seeks manuscripts that offer pathobiological and translational impact to inform the personal, clinical, and societal problems posed by cancer. The main scope of the journal is captured in its primary subsections:
/// Genome and Epigenome
/// Metabolism and Chemical Biology
/// Molecular Cell Biology
/// Tumor Biology and Immunology
/// Translational Science
/// Convergence and Technologies
/// Population and Prevention Science
The following criteria provide an overview of the types of studies considered by the journal:
/// Findings that have not been previously published in another tumor model.
/// Studies performed in multiple cell lines.
/// Conclusions that are not representative of incremental findings.
/// Studies that include a clearly written title and abstract that communicate the study's impact of significance to non-experts.
/// An incisive rationale that could interest a broad audience.
/// Manuscripts containing in vivo data. Although in vivo data is not required, studies containing this data are preferred.
/// A potentially generalizable, broad impact conclusion.
/// Studies that describe RNA interference (RNAi) must contain one non-specific control and two specific siRNAs for each knockdown target of interest. Additional data is required that demonstrates knockdown achievement at the level of protein expression (not just mRNA).